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doi: 10.1016/j.bone.2020.115553 27 HansenMSSeKChristensenLLFernandez-GuerraPHansenNWWyattRAet al

Preclinical studies have suggested that it influences gene accessibility and transcriptional activity

Those who were FRAA-positive had even greater benefit, with a large effect size (Cohen's d = 0.91)

Best For Recommendations# Maximum Weight Loss# Recommendation : Retatrutide Reason : Phase 3 TRIUMPH-4 showed 28.7% weight loss at 68 weeks, substantially exceeding CagriSema's 20.4% at 68 weeks

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